Influencing factors of Barrett's esophagus after endoscopic submucosal dissection in patients with early esophageal cancer
10.3969/j.issn.1005-6483.20231317
- VernacularTitle:早期食管癌病人内镜下黏膜剥离术后Barrett食管发生的影响因素
- Author:
Zhen ZHANG
1
;
Lin LIU
1
;
Yiyao ZHU
1
;
Xiaobo WU
1
Author Information
1. 214000 南京医科大学附属无锡人民医院/无锡市人民医院胸外科,南京医科大学无锡医学中心
- Publication Type:Journal Article
- Keywords:
esophageal carcinoma;
endoscopic submucosal dissection;
Barrett's esophagus;
influencing factors
- From:
Journal of Clinical Surgery
2025;33(1):89-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influencing factors of Barrett's esophagus after endoscopic submucosal dissection(ESD)in patients with early esophageal cancer.Methods 110 patients with esophageal cancer who received ESD therapy in our hospital from January 2022 to March 2023 were divided into two groups according to whether they had Barrett's esophagus(n=20)and no Barrett's esophagus(n=90).The general clinical data,esophageal cancer related characteristics and ESD related treatment characteristics of the two groups were compared.Multivariate regression analysis were used to screen the risk factors of Barrett's esophagus in patients with esophageal cancer after ESD.Results The proportion of male,former drinking,former smoking,prevalence of peptic ulcer,multiple tumors,maximum diameter of tumors,the rate of postoperative lymph node metastasis,postoperative distant metastasis and the proportion of muscularis propria injury in patients with Barrett's esophagus were significantly higher(P＜0.05).Multivariate logistic regression analysis showed that alcohol drinking,smoking,peptic ulcer,postoperative lymph node metastasis,postoperative distant metastasis and injury of muscularis propria were the risk factors for Barrett's esophagus(P＜0.05).Conclusion Patients with a history of drinking,smoking,peptic ulcer,postoperative lymph node metastasis,postoperative distant metastasis and injury of muscularis propria are more likely to develop Barrett's esophagus after ESD.
