Therapeutic effect of the treatment combined with hyperbaric oxygen on 36 patients with herpes zoster
10.3760/cma.j.cn311847-20200819-00328
- VernacularTitle:高压氧综合治疗带状疱疹36例疗效观察
- Author:
Xu YANG
1
;
Jinting CHU
;
Shilong SUN
;
Weimin ZHOU
;
Nana LIN
;
Shan MENG
;
Fanchao MENG
;
Xijing WANG
Author Information
1. 450006 郑州，郑州市第二人民医院高压氧科
- Publication Type:Journal Article
- Keywords:
Herpes zoster;
Hyperbaric oxygen;
Skin lesion improvement;
Pain score
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2021;28(1):61-63,73
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical effect of the treatment combined with hyperbaric oxygen (HBO) on patients with herpes zoster.Methods:A total of 72 patients with herpes zoster treated in the Department of Dermatology of Zhengzhou Second Hospital from January 2018 to December 2019 were selected and divided into HBO group and control group by random number table method, with 36 patients in each group. The control group received acyclovir and other conventional treatments, while the HBO group received HBO on the basis of the treatments of the control group. The improvement of the skin lesions, scores of numeric rating scales (NRS) on pain, and efficacy of the two groups were observed and evaluated after treatment. After a 3-month follow-up, the occurrence of postherpetic neuralgia (PHN) was statistically analyzed.Results:The time of blistering relieving, incrustation, and complete incrustation of the HBO group were all lower than those of the control group with statistically significant difference ( P<0.05). The NRS scores of both groups were all lower than those before treatment with significantly statistical difference ( P<0.01); and the NRS scores of the HBO group were significantly lower than those of the control group after treatment ( P<0.05). The total effective rate of the HBO group (91.67%) was significantly higher than that of the control group (83.33%). The difference was statistically significant ( χ2=4.31, P=0.04). After treatment, 3 cases of PHN occurred in the HBO group, while 7 cases in the control group; the PHN incidence of the HBO group was lower than that of the control group with significantly statistical difference ( P<0.05). Conclusion:In treating herpes zoster, the treatment combined with HBO can achieve a satisfactory therapeutic effect, which is worthy of popularization and application in clinic.
