Experimental study on rapid Identification of Compressed Laughing Gas and its Purity With GC-MS
10.13618/j.issn.1001-5728.2025.01.011
- VernacularTitle:应用GC-MS快速鉴定压缩笑气及其纯度的实验研究
- Author:
Shengxiang WANG
1
;
Jinglu BI
;
Peng WU
;
Huiya YUAN
;
Enyu XU
;
Junting LIU
Author Information
1. 河北中石油中心医院,河北 廊坊 065000;中国医科大学法医学院,辽宁 沈阳 110001
- Publication Type:Journal Article
- Keywords:
Laughing gas;
Carbon dioxide;
GC-MS;
Rapid identification;
Purity
- From:
Chinese Journal of Forensic Medicine
2025;40(1):61-64,69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate a rapid detection method for compressed Nitrous oxide(N2O).Methods The GC-MS system was employed under conventional chromatographic conditions(without replacing standard columns or utilizing headspace sampling)by directly injecting a small gas sample for analysis.N2O identification was performed via NIST spectral library matching,while qualitative and quantitative purity assessments were achieved by monitoring the relative abundance variation of the characteristic fragment ion m/z 30 to eliminate CO2 interference.Results The fragment ion m/z 30 demonstrated specificity for N2O identification.A linear correlation was observed between the peak area of m/z 30 and N2O purity(y=22.741x-1.4565,R2=0.912 6),enabling quantitative purity determination.Additionally,the abundance of m/z30 exhibited a correlation with N2O in CO2 mixtures(y=0.7787x-0.0387,R2=0.722 2).Conclusion Conventional N2O identification typically requires dedicated GC-MS systems,gas-specific chromatographic columns,and headspace sampling.This study successfully utilized routine chromatographic conditions for organic toxicant screening to achieve rapid N2O analysis.The proposed method holds practical significance for compressed N2O identification in forensic and analytical applications.
