Progress of Quantitative Counting of Enteric Nervous System in Constipation
10.3969/j.issn.1008-7125.2024.08.009
- VernacularTitle:肠神经系统定量计数在便秘中的研究进展
- Author:
Gaoyuan TIAN
1
;
Bin KONG
1
;
Qiang CHEN
1
;
Bo WANG
1
;
Shipeng ZHAO
1
Author Information
1. 河北医科大学第三医院胃肠外科(050051)
- Publication Type:Journal Article
- Keywords:
Enteric Nervous System;
Quantitative Counting;
Constipation;
Immunohistochemistry
- From:
Chinese Journal of Gastroenterology
2024;29(8):505-510
- CountryChina
- Language:Chinese
-
Abstract:
Changes in the enteric nervous system(ENS)play a critical role in the generation and development of constipation.Chronic constipation is thought to be largely caused by the lack or deterioration of enteric nerve cells.At present,most domestic and foreign medical institutions still rely on paraffin pathological sections for the identification and detection of ENS in patients with constipation.However,even major ENS defects are difficult to precisely identify in pathological sections of the human gut.Therefore,studying new technologies that can better visualize ENS is a crucial link in exploring the relevant development mechanisms of constipation.This review reviews the development venation of quantitative studies on ENS in the past two decades,and discusses the relationship between quantitative data on ENS and various types of constipation.This article reviewed the methods of recognition and detection of the ENS,hoping to provide more stable observation criteria,and then help explore the mechanism of the generation and development of constipation.
