Study on the correlation between the serum uric acid levels and ischemic stroke in young people
10.3760/cma.j.cn101721-20240319-00077
- VernacularTitle:血尿酸水平与青年缺血性脑卒中的相关性研究
- Author:
Junchao LI
1
;
Hongjun SU
1
Author Information
1. 天津医科大学附属宝坻医院神经内科，天津 301800
- Publication Type:Journal Article
- Keywords:
Ischemic stroke, youth;
Serum uric acid;
Prognosis
- From:
Clinical Medicine of China
2025;41(1):32-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the level of serum uric acid in young patients with ischemic stroke, and to explore the relationship between the level of serum uric acid and the short-term prognosis of young patients with ischemic stroke.Methods:From July 2020 to December 2022, 93 cases of young patients with ischemic stroke admitted to the Department of Neurology of Tianjin Baodi Hospital were collected as the case group, and 93 cases of healthy people in the physical examination center during the same period were collected as the control group. The clinical data of the two groups were collected and analyzed retrospectively, and the uric acid level of the two groups was compared, and the influence of serum uric acid level on the short-term prognosis of young patients with ischemic stroke was discussed. The measurement data of normal distribution were compared by two independent samples t-test, the measurement data of non-normal distribution were represented by xˉ± s and compared by non-parametric rank sum test, and the count data were represented by M( Q1, Q3) compared by chi-square test, the relationship between uric acid and short-term exacerbation of acute ischemic stroke in young patients was analyzed by binary Logistic multivariate analysis. Results:There was no significant difference in serum uric acid between case group and control group ( P>0.05), The level of serum uric acid in young patients with ischemic stroke in short-term exacerbation group (316.54±128.18) μmol/L was lower than that in stable group (388.62±113.54) μmol/L. The difference was statistically significant ( t=2.21, P=0.030). Conclusion:Elevated serum uric acid level is not an independent risk factor of ischemic stroke in young people, and serum low uric acid level is associated with short-term aggravation of acute ischemic stroke.
