Chemical constituents from the stems and barks of Maytenus variabilis
10.3969/j.issn.1001-1528.2025.05.019
- VernacularTitle:刺茶美登木茎枝化学成分研究
- Author:
Ting HE
1
;
Bing-qian LIU
1
;
Jian-feng CHEN
1
;
Xiao-qin YU
1
;
Cheng-xiong LIU
1
;
Kun ZOU
1
;
Fan CHENG
1
Author Information
1. 三峡大学生物与制药学院,天然产物研究与利用湖北省重点实验室,湖北宜昌 443002
- Publication Type:Journal Article
- Keywords:
Maytenus variabilis(Hemsl.)C.Y.Cheng;
stems and barks;
chemical constituents;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2025;47(5):1539-1547
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from the stems and barks of Maytenus variabilis(Hemsl.)C.Y.Cheng.METHODS The 95％ethanol extract from the stems and barks of M.variabilis was isolated and purified by silica gel,Sephadex LH-20 and semi preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-three compounds were isolated and identified as β-amyrin(1),3β-acetoxyolean-12-en-11-one(2),ursa-12-ene-11-one-3-ol octocosate(3),friedelin(4),canophyllol(5),pinoresinol(6),medioresinol(7),isolariciresinol(8),dihydrodehydrodiconiferyl alcohol(9),vanillic acid(10),7R,8S-5-methoxydihydrodehydroconiferyl alcohol(11),β-hydroxypropiovanillone(12),triptregeline B(13),triptregeline E(14),(+)-evofolin B(15),2,5-dimethoxybenzoquinone(16),olean-12-ene-3,11-dione(17),β-sitosterol(18),(-)-(7R,7'R,7"S,8S,8'S,8"S)-4',4"-dihydroxy-3,3',3",5-tetramethoxy-7,9',7',9-diepoxy-4,8"-oxy-8,8'-sesquineolignan-7",9"-diol(19),phyllostadimer B(20),rayalinol(21),lyoniresinol(22),dihydrobuddlenol B(23).CONCLUSION Compounds 3,9-11,13-14,16,19-21,23 are isolated from genus Maytenus for the first time,and compounds 2,4-5,7-8,12,15,17,22 are first found from this plant.
