Effects of rice wine type and wine processing method on chemical constituents and anti-coagulation effect of Angelicae sinensis Radix
10.3969/j.issn.1001-1528.2025.05.005
- VernacularTitle:黄酒类型和酒制方法对当归化学成分、抗凝血作用的影响
- Author:
Ying WANG
1
;
Ya-yi DENG
;
Xue-qi GE
;
Hui ZHU
;
Yu DUAN
;
Xiao-ning YAN
;
Hao CAI
;
Ke PEI
Author Information
1. 南京中医药大学药学院,国家教育部中药炮制规范化及标准化工程研究中心,江苏南京 210023
- Publication Type:Journal Article
- Keywords:
Angelicae sinensis Radix;
rice wine;
type;
wine processing method;
chemical constituents;
anti-coagulation effect;
HPLC
- From:
Chinese Traditional Patent Medicine
2025;47(5):1443-1448
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the effects of rice wine type and wine processing method on chemical constituents and anti-coagulation effect of Angelicae sinensis Radix.METHODS Wine-washed products and wine-stir-fried products were prepared by different types and ages of rice wine,respectively,after which HPLC was adopted in the content determination of tryptophan,chlorogenic acid,vanillic acid,phthalic acid,ferulic acid,senkyunolide I,senkyunolide H,coniferyl ferulate and ligustilide,and PT,APTT,TT were detected in rabbit plasma.RESULTS Phenolic acids and volatile constituents demonstrated lower contents in the wine-stir-fried products than those in the raw product(P＜0.05),while those in the wine-washed products displayed no obvious changes(except for senkyunolide I)(P＞0.05).The contents of volatile constituents in the wine-washed products were higher than those in the wine-stir-fried products(P＜0.05).After being processed with dry rice wine,various constituents exhibited increased contents as compared with those after being processed with sweet rice wine(P＜0.05).Compared with the raw product,prolonged PT,APTT and TT were observable in the processed products prepared by 3-year semi-dry rice wine(P＜0.05).CONCLUSION The optimal rice wine type is determined to be 3-year semi-dry.Wine-washed Angelicae sinensis Radix shows high contents of ferulic acid and volatile constituents,whose activating blood and resolving stasis effect may be stronger.
