Research advances in immunotherapy for acute myeloid leukemia
10.12354/j.issn.1000-8179.2025.20250399
- VernacularTitle:急性髓系白血病的免疫治疗研究进展
- Author:
Li TIANTIAN
1
;
Kong FANCONG
1
Author Information
1. 南昌大学江西医学院第一附属医院血液病中心,江西省血液病临床医学研究中心,血液系统疾病江西省重点实验室(南昌市 330006)
- Publication Type:Journal Article
- Keywords:
acute myeloid leukemia(AML);
immunotherapy;
research advances
- From:
Chinese Journal of Clinical Oncology
2025;52(7):354-360
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemia(AML)is a hematological malignancy.For decades,chemotherapy has remained the mainstay of AML treatment.With the application of targeted therapy in recent years,the treatment landscape of AML has changed.However,some patients exhibit resistance to treatment or relapse after treatment.Therefore,novel,highly effective,and low-toxicity regimens must be explored in order to further improve the clinical outcomes of patients.Immunotherapy achieves anti-tumor treatment by modulating the body's im-mune response.It has demonstrated considerable efficacy and controllable safety in relapsed or refractory patients;thus,it is expected to serve as an important therapeutic option for this group of patients.In this article,we review the research advances in immunotherapy for AML treatment.