New technology for early screening of Alzheimer's disease in community-oriented primary care
10.3969/j.issn.1004-1648.2025.01.017
- VernacularTitle:适用于社区场景的Alzheimer's病早期筛查新工具
- Author:
Jialiu JIANG
1
;
Yuting MO
1
;
Siyuan ZHANG
1
Author Information
1. 210008 南京大学医学院附属鼓楼医院神经内科
- Publication Type:Journal Article
- Keywords:
Alzheimer's disease;
early diagnosis;
biosensor;
digital biomarker
- From:
Journal of Clinical Neurology
2025;38(1):70-73
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease(AD)is a neurodegenerative disease characterized by cognitive impairment,loss of life function,mental and behavioral abnormalities.It is the leading cause of dementia in the elderly.The prevalence of mild cognitive impairment(MCI)in the elderly over 60 years old in China is 15.5％,and the prevalence of AD is 3.9％,which becomes a major public health challenge for China to enter the rapid growth stage of aging.Early diagnosis and early intervention are the keys to improving the prognosis of AD and reducing mortality.MCI is an important window for early intervention of AD,but how to detect MCI in the community conveniently and economically remains to be explored.This article reviews the research progress of biosample-based biosensors,retinal imaging,and digital biomarkers,and provides conceptual ideas for AD screening in community-oriented primary care.
