Clinical Analysis of alpha-Fetoprotein-producing Gastric Cancer
10.3969/j.issn.1008-7125.2024.11.007
- VernacularTitle:甲胎蛋白阳性胃癌的临床分析
- Author:
Lu NIU
1
;
Shujuan GAO
1
;
Yifei LÜ
1
;
Xue WANG
1
;
Ting QIU
1
;
Yu ZHANG
1
;
Guisheng LIU
1
Author Information
1. 陕西省人民医院消化内一科(710068)
- Publication Type:Journal Article
- Keywords:
Stomach Neoplasms;
alpha-Fetoprotein;
Diagnosis;
Therapy;
Prognosis
- From:
Chinese Journal of Gastroenterology
2024;29(11):682-684
- CountryChina
- Language:Chinese
-
Abstract:
Background:alpha-fetoprotein-producing gastric cancer(AFPGC)is relatively rare and special type of gastric cancer,and its clinical symptoms are lack specificity.Aims:To summarize the clinical characteristics and prognosis of AFPGC.Methods:The data of patients with AFPGC from July 2017 to June 2023 at Shaanxi Provincial People's Hospital were retrospectively analyzed,including clinical manifestations,laboratory and examination results,endoscopic results,pathology and treatment.Results:In 17 patients with AFPGC,14 were male and 3 were female.The clinical manifestations were mainly abdominal pain,hematochezia,upper abdominal discomfort,fatigue,etc.AFP was 200-2000 ng/mL.The laboratory examination tests showed that anemia in 16 patients,elevated CEA in 1 patient,abnormal liver function in 2 patients,Hepatitis B Virus-positive in 1 patient,CT showed liver metastasis in 11 patients,lymph node metastasis in 12 patients,cirrhosis in 1 patient.Conclusions:For patients with gastric cancer indicated by examination,if AFP is elevated,AFPGC should be considered.Early detection and surgical treatment can improve the prognosis of AFPGC.
