Analysis on the Current Status of Clinical Trial Registration of TCM for the Treatment of Cervical Spondylosis
10.19879/j.cnki.1005-5304.202407597
- VernacularTitle:中医药治疗颈椎病临床试验注册现状分析
- Author:
Congyang XUE
1
;
Nan WANG
;
Heng CHEN
;
Shuang CHEN
;
Xin LIU
;
Lin XIE
Author Information
1. 南京中医药大学附属中西医结合医院,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
cervical spondylosis;
clinical trial registration;
traditional Chinese medicine
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(8):63-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide references for the registration and implementation of related clinical trials by analyzing the current status of clinical trial registration of TCM for the treatment of cervical spondylosis.Methods Relevant clinical trials of TCM for the treatment of cervical spondylosis were retrieved from China Clinical Trial Registry,International Clinical Trial Registry Platform and US Clinical Trials Registry database from the establishment to 1 July 2024.The relevant data were extracted and entered into Excel 2019,and GraphPad Prism 9.0 was used to statistically analyse the registration characteristics of clinical trials of TCM for the treatment of cervical spondylosis.Results A total of 126 clinical trials of TCM for the treatment of cervical spondylosis were included in this study,of which 112 were interventional studies.Domestic registrations covered a total of 19 provincial administrative regions,with the top two being Shanghai and Guangdong Province.The research on disease types included all subtypes of cervical spondylosis,with the largest number of registered items(37 items,29.37%)related to cervical spondylostic radiculopathy,followed by projects with unspecified cervical spondylosis subtypes(44 projects,34.92%).Research projects from universities and affiliated hospitals accounted for 89.7%(113 projects),with Guangdong Provincial Hospital of Traditional Chinese Medicine(12 projects)registering the most projects.Totally 110 research projects were funded,with local financial support accounting for 39.09%(43 projects)and national financial support accounting for 16.36%(18 projects).The study designs were mainly randomized parallel controlled studies(112 projects,88.9%),mostly single-centre research projects(92 projects,73.0%),with sample sizes concentrated between 50-200(86 projects,68.3%).The interventions were mostly external TCM treatments,such as acupuncture(41 items,32.5%)and tuina(23 items,18.3%).Conclusion The number of registered clinical trials of TCM for the treatment of cervical spondylosis has shown a fluctuating upward trend,but there are problems such as a small number,uneven geographical development,low methodological quality,mostly single-centre trials,and a lack of projects with Chinese materia medica intervention projects.
