Arrhythmia and hypokalemia induced by mistaken use of overdose of procaterol in a child
10.3760/cma.j.cn114015-20241008-00080
- VernacularTitle:误服过量盐酸丙卡特罗致儿童心律失常和低钾血症
- Author:
Dongli ZHI
1
;
Wei HE
1
;
Cui ZHU
1
Author Information
1. 河南省信阳市商城县中医院儿科，商城 465350
- Publication Type:Journal Article
- Keywords:
Adrenergic beta-agonists;
Procaterol;
Child;
Medication errors;
Hypokalemia;
Ventricular premature beat
- From:
Adverse Drug Reactions Journal
2025;27(6):375-377
- CountryChina
- Language:Chinese
-
Abstract:
A 9 years and 8 months old girl was prescribed procaterol hydrochloride oral solution (procaterol) 25 μg (5 ml) twice daily for cough and asthma. The girl mistakenly took 25 ml of procaterol because her grandmother thought it was 25 μg. After 30 minutes, the girl developed restlessness, shortness of breath, trembling hands, and vomiting. Physical examination showed heart rate 148 beats/min, cardiac auscultation showed arrhythmia, electrocardiogram showed frequent ventricular premature beat, and laboratory tests showed blood potassium 2.5 mmol/L. Procaterol poisoning was considered. Oxygen inhalation, electrocardiographic monitoring, metoprolol tartrate tablets 25 mg orally, and symptomatic and supportive treatments such as coenzyme A, adenosine triphosphate, and potassium chloride, were given immediately. Two hours alater, the child′s restlessness disappeared and shortness of breath was improved; the electrocardiogram reexamination showed no ventricular premature beat. Ten hours later, the heart rate returns to normal. The next day, her blood potassium level returned to normal.
