Vertebroplasty combined with microwave ablation for treating vertebral compression fractures caused by metastatic cancer
10.13929/j.issn.1672-8475.2025.01.003
- VernacularTitle:椎体成形术联合微波消融治疗转移癌致椎体压缩性骨折
- Author:
Yuanyuan QIU
1
;
Chao XING
1
;
Qianqian YUAN
1
;
Kaixian ZHANG
1
;
Xusheng ZHANG
1
Author Information
1. 济宁医学院附属滕州市中心人民医院肿瘤科,山东 滕州 277500
- Publication Type:Journal Article
- Keywords:
fractures,compression;
neoplasm metastasis;
vertebroplasty;
microwave ablation
- From:
Chinese Journal of Interventional Imaging and Therapy
2025;22(1):11-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of percutaneous vertebroplasty(PVP)combined with microwave ablation(MWA)for treating vertebral compression fractures(VCF)caused by metastatic cancer.Methods Totally 112 patients with VCF caused by metastatic cancer were retrospectively enrolled,including 77 cases(105 vertebrae)underwent MWA+PVP(group A)and 35 cases(68 vertebrae)who underwent PVP alone(group B).The success rates of the treatments were recorded,and complications were observed.Visual analogue scale(VAS)score of pain,daily morphine consumption(DMC)and Oswestry disability index(ODI)of patients were compared within and between groups after treatments,and local tumor recurrence rates after treatment were observed.Results The success rates of MWA and PVP were both 100%.After treatments,bone cement leakage occurred in 12 cases(12/77,15.58%)in group A and 19 cases(19/35,54.29%)in group B,in group A was lower than in group B(P＜0.001).No other complications occurred.One week and 1,3 and 6 months after treatments,VAS scores of pain,DMC and ODI in group A and B were all lower than those before treatments(all P＜0.001).Three and 6 months after treatments,VAS scores of pain in group A were lower than those in group B(both P＜0.01),while 6 months after treatments,DMC and ODI in group A were lower than those in group B(both P＜0.01).No significant difference of VAS scores of pain,DMC nor ODI was found between groups at the other time points(all P＞0.05).Six months after treatments,local tumor recurrence rate in lesions in group A(17.14%,18/105)was significantly lower than that in group B(32.35%,22/68)(P=0.020).Conclusion For treating VCF caused by metastatic cancer,PVP combined with MWA could reduce incidence of complications,prolong pain relief time and bring better short-term local tumor control effect.
