Transesophageal echocardiography combined with agitated saline contrast echocardiography for identifying morphological features of high-risk patent foramen ovale and evaluating risk of related stroke
10.13929/j.issn.1003-3289.2025.04.020
- VernacularTitle:经食管超声心动图联合右心声学造影识别高危卵圆孔未闭形态特征并评估相关性卒中风险
- Author:
Xin LI
1
;
Yanbin REN
1
;
Huan ZHANG
1
;
Juntong HU
1
;
Danni ZHANG
1
;
Lixiang AN
1
Author Information
1. 邯郸市中心医院超声医学科,河北 邯郸 056001
- Publication Type:Journal Article
- Keywords:
foramen ovale,patent;
stroke;
echocardiography,transesophageal
- From:
Chinese Journal of Medical Imaging Technology
2025;41(4):602-605
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the feasibility of transesophageal echocardiography(TEE)combined with agitated saline contrast echocardiography(ASCE)for identifying morphological characteristics of high-risk patent foramen ovale(PFO)and evaluating the risk of PFO related stroke.Methods Totally 212 PFO patients diagnosed by TEE combined with ASCE were enrolled,including 100 cases with cryptogenic stroke(CS)(CS group)and 112 without CS(non-CS group).Anatomical morphological characteristics of PFO were comparatively analyzed between groups to screen the independent factors of CS.Results In CS group,the left and right atrial opening diameters of PFO were all larger than those in non-CS group in both resting-state and stimulated state.The aortic root diameter in CS group was larger than that in non-CS group,and the incidence of atrial septal aneurysm(ASA),high activity of the atrial septum,inferior vena cava valve or Chiari network,large amount of right-to-left-shunt(RLS)in stimulated state,and multiple outlets of the oval valve in CS group were all higher than those in non-CS group(all P＜0.05).Logistic regression analysis showed that ASA,high atrial septal activity,large amount of RLS and multiple oval valve outlets were all independent factors associated with CS(OR=0.211,0.384,0.999,0.199,all P＜0.05).Conclusion TEE combined with ASCE could identify anatomical characteristics of high-risk PFO and assess the risk of PFO related stroke.
