Meta-analysis of efficacy and safety of Bailemian capsule in the treatment of stroke-related sleep disorder
10.3969/j.issn.1673-9701.2025.13.014
- VernacularTitle:百乐眠胶囊治疗卒中相关睡眠障碍的疗效及安全性Meta分析
- Author:
Chujiong CHEN
1
;
Chengtong BAO
;
Shuhua YUE
;
Zengyu ZHANG
;
Jiamin CHEN
;
Yanni XIAO
Author Information
1. 湖南中医药大学中医学院,湖南长沙 410208
- Publication Type:Journal Article
- Keywords:
Bailemian capsule;
Stroke-related sleep disorder;
Meta-analysis
- From:
China Modern Doctor
2025;63(13):60-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of Bailemian capsule in the treatment of stroke-related sleep disorder(SSD).Methods The relevant literatures published by CNKI,VIP,Wanfang Data Knowledge Service Platform,SinoMed,PubMed,Web of Science,Cochrane Library database were retrieved from the establishment of the database to December 21,2024.Cochrane risk bias assessment tool was used to evaluate the literature quality,and RevMan 5.3 software was used to conduct Meta-analysis of the included literatures.Results A total of 11 literatures and 1054 patients were included.The results of Meta-analysis showed that cure and significant efficiency rate of patients of bservation group were significantly higher than those of control group(OR=1.93,95％CI:1.50-2.48,P＜0.000 01),clinical effective rate was significantly higher than that of control group(OR=3.70,95％CI:2.50-5.49,P＜0.000 01),incidence of adverse reactions was significantly lower than that of control group(OR=0.38,95％CI:0.22-0.67,P=0.0007).Conclusion Western medicine treatment combined with Bailemian capsule can reduce the insomnia symptoms of SSD patients,effectively improve the quality of life,and have good safety.
