Analysis of Animal Models of Acute Appendicitis Based on Clinical Symptoms of Traditional Chinese and Western Medicine
10.11842/wst.20240103011
- VernacularTitle:基于中西医临床病症特点的急性阑尾炎动物模型分析
- Author:
Shuo NAN
1
;
Huanhuan GONG
1
;
Yuanxin ZHANG
1
;
Xiumin LI
1
;
Mingsan MIAO
1
Author Information
1. 河南中医药大学药学院 郑州 450046
- Publication Type:Journal Article
- Keywords:
Acute appendicitis;
Animal model;
Traditional Chinese and western medicine;
Clinical features
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2024;26(12):3234-3239
- CountryChina
- Language:Chinese
-
Abstract:
Objective Acute appendicitis is a common clinical emergency.In traditional Chinese medicine,the famous Fang Dahuang Mudan Decoction has been recorded for the treatment of appendicitis.Therefore,this paper summarizes the animal models of acute appendicitis,evaluates the clinical consistency,and puts forward suggestions for improvement.Methods By searching databases such as CNKI,Wanfang and Pubmed,the animal models of acute appendicitis were summarized,assigned to each model and evaluated for clinical fit.Results The five models of appendix and arteriovenous ligation,appendix ligation,appendix ligation and perforation,bacteria injection,and hydrochloric acid injection were all highly consistent.Most of the five modeling methods are based on Western medicine modeling methods,and basically do not involve TCM syndrome types.Conclusion On the basis of five modeling methods,with the intervention of TCM stasis syndrome,damp-heat syndrome,and heat-toxin syndrome factors,an integrated TCM and Western medicine model that reflects TCM syndrome types can be prepared.Taking animal models with TCM syndromes as a carrier is more conducive to the research and development of TCM.
