Research Progress on the Mechanism of Improving Aplastic Anemia by Traditional Chinese Medicine Formulas and Ingredients
- VernacularTitle:中药复方及成分改善再生障碍性贫血机制研究进展
- Author:
Yuying LIANG
1
;
Wanruo WAN
;
Yan XIE
;
Liuliu QIN
;
Haoli QIN
;
Erwei HAO
;
Zhengcai DU
;
Jiagang DENG
;
Xiaotao HOU
Author Information
- Publication Type:Journal Article
- Keywords: Hematopoietic stem/progenitor cells abnormality; Immune abnormality; Bone marrow microenvironment abnormality; Traditional Chinese medicine compound; Traditional Chinese medicine ingredients
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(1):168-178
- CountryChina
- Language:Chinese
- Abstract: Aplastic anemia is a rare and life-threatening bone marrow failure that is becoming more common and tends to affect younger individuals.Traditional Chinese medicine has a long history of preventing and treating asthenia and blood syndrome.Its treatment of aplastic anemia involves coordinated regulation through multiple components,targets,and channels.The article classifies and elaborates on the therapeutic effects of traditional Chinese medicine compounds and their components on aplastic anemia.As well as the expression of related factors from three aspects:hematopoietic stem/progenitor cells,the immune system,and bone marrow microenvironmental abnormalities.It also analyzes the frequency and meridian of commonly used drugs in traditional Chinese medicine compounds.Deficiency tonifying drugs were found to be the most frequently used treatment for aplastic anemia,which is consistent with the deficiency-based nature of the disease.The related organs affected are the liver,spleen,and kidney.This paper reviews the mechanism of aplastic anemia and the preventive and therapeutic effects of traditional Chinese medicine.The study is of great significance for the follow-up research on traditional Chinese medicine in improving aplastic anemia.
