Death due to severe hypoglycemia caused by diclofenac sodium and lidocaine injection
10.3760/cma.j.cn114015-20201120-01163
- VernacularTitle:双氯芬酸钠利多卡因注射液诱发严重低血糖致死亡
- Author:
Jinyan TANG
1
;
Peipei LU
1
;
Hui YANG
1
;
Hui QIAN
1
;
Junzuan XI
1
;
Jinhua SHEN
1
Author Information
1. 江苏省如皋市人民医院药剂科，如皋 226500
- Publication Type:Journal Article
- Keywords:
Diclofenac;
Lidocaine;
Hypoglycemia;
Death
- From:
Adverse Drug Reactions Journal
2021;23(6):324-325
- CountryChina
- Language:Chinese
-
Abstract:
A 53-year-old male patient received intramuscular injection of diclofenac sodium and lidocaine injection 2 ml for abdominal pain. After one hour of medication, the patient developed upper abdominal discomfort, chest tightness, shortness of breath, sweating, and slight cyanosis of lips. Oxygen inhalation was given immediately. Electrocardiogram monitoring showed blood pressure 105/60 mmHg, heart rate 125 beats/min, and blood oxygen saturation 0.75. His peripheral blood glucose could not be detected. Glucose supplement and hormone therapy were given immediately. About 30 minutes later, the patient developed unconsciousness, no pulsation of the main artery, and cardiac and respiratory arrest. Cardiopulmonary resuscitation and other treatment measures were given immediately. However, the patient did not return to spontaneous heartbeat and breathing and was declared dead. It was considered that the patient′s severe hypoglycemia might be related to diclofenac sodium and lidocaine.
