Adropin level and its correlation with collateral circulation status in elderly patients with acute myocardial infarction
10.3969/j.issn.1009-0126.2025.05.011
- VernacularTitle:老年急性心肌梗死患者能量平衡相关蛋白抗体水平及其与侧支循环状态的相关性
- Author:
Jingfang GAO
1
;
Haixia CHAI
;
Li LI
;
Xuebin GENG
;
Yi MA
;
Fan JIA
Author Information
1. 063000 唐山市工人医院心内二科
- Publication Type:Journal Article
- Keywords:
myocardial infarction;
collateral circulation;
erythrocyte indices;
forecasting
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(5):592-595
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the level of energy balance related protein antibody,adropin,and its correlation with collateral circulation status in elderly patients with AMI.Methods A total of 193 elderly AMI patients admitted to our department from February 2022 to February 2024 were enrolled,and based on their collateral circulation status,they were divided into a good circulation group(121 cases)and a poor circulation group(72 cases).The level of adropin was determined.Multivariate logistic regression analysis was employed to determine the influencing factors of poor collateral circulation in elderly AMI patients.Results The poor circulation group had significantly larger proportion of hypertension,higher fasting blood glucose(FBG),and larger red blood cell distribution width(RDW),but lower adropin level and mean platelet volume(MPV)when com-pared with the good circulation group(P＜0.05,P＜0.01).Multivariate logistic regression analy-sis showed that adropin,FBG,RDW,MPV,and hypertension were all influencing factors for poor collateral circulation in elderly AMI patients(P＜0.05,P＜0.01).The AUC value of adropin,FBG,RDW,MPV,and hypertension was 0.810,0.762,0.761,0.715 and 0.563,respectively in pre-dicting poor collateral circulation.Among them,adropin level had the highest predictive value(P＜0.01).Conclusion The decrease in adropin level in elderly AMI patients is closely associated with poor collateral circulation,and it is a predictive factor for collateral circulation.
