Imaging Features of Juvenile Xanthogranuloma in Children
10.3969/j.issn.1005-5185.2024.12.005
- VernacularTitle:儿童幼年性黄色肉芽肿的影像学表现
- Author:
Qiuhong MA
1
;
Yiwei YIN
1
;
Siping HE
1
;
Yonghua XIANG
1
;
Ke JIN
1
Author Information
1. 中南大学湘雅医学院附属儿童医院(湖南省儿童医院)放射科,湖南 长沙 410007
- Publication Type:Journal Article
- Keywords:
Xanthogranuloma,juvenile;
Children;
Tomography,X-ray computed;
Magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging
2024;32(12):1222-1227,1230
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To analyze the imaging features of juvenile xanthogranuloma (JXG) in children and to improve the diagnostic level of JXG. Materials and Methods The clinical and imaging data of 15 children with JXG confirmed by menstrual biopsy or surgical pathology from January 2011 to December 2023 in Hunan Children's Hospital were retrospectively analyzed. 13 cases underwent CT examinations and 7 cases underwent MRI examinations,of which 5 underwent both MRI and CT examinations. The type,number,involved site,lesion signal,density and enhancement characteristics of JXG were observed and analyzed. Results Of the 15 children with JXG,7 cases were systemic. It involves the central nervous system (5 cases,including pineal region,choroid plexus,cranial sublamina,middle cranial fossa and spinal canal),mastoid process (1 case),liver (3 cases),kidney (3 cases),pancreas (1 case) and lung (2 cases),mainly manifested as single or multiple nodular,mass or patchy lesions in different organs. On MRI,the lesions showed slightly higher or lower or mixed signals on T1WI,low/slightly lower or higher or mixed signals on T2WI,unrestricted or limited diffusion,and significantly enhanced or slightly enhanced enhancement. On CT,the lesions showed patchy,clumpy or nodular low-density or high-density shadows,and the enhancement was mild to moderate uneven enhancement or obvious enhancement. 8 patients with simple skin type showed nodular shadow of subcutaneous soft tissue,equal or slightly low signal on T1WI,slightly low/low signal on T2WI and obvious enhancement. CT showed a slightly low/equal/slightly high density image,and the enhancement showed a slightly enhanced/significantly enhanced image. Conclusion JXG mainly presents as single or multiple nodules and clumps in subcutaneous soft tissues and/or various organs,with increased signal on T1WI,decreased signal on T2WI,decreased or increased diffusion and obvious enhancement. The CT and MRI manifestations of JXG have certain characteristics.
