Evaluation of ultrasound scoring system combined with shear wave elastography on curative effect of IgG4-related submandibular and lacrimal gland inflammation
10.3969/j.issn.1672-8270.2025.05.003
- VernacularTitle:超声评分系统联合剪切波弹性成像评价IgG4相关颌下腺炎及泪腺炎的疗效
- Author:
Jinhuai ZHANG
1
;
Mingzhu ZHOU
;
Yanying LIU
;
Xiangdong HU
Author Information
1. 首都医科大学附属友谊医院超声科 北京 100050;北京市海淀医院 北京大学第三医院海淀院区超声科 北京 100080
- Publication Type:Journal Article
- Keywords:
Shear wave elastrography(SWE);
Ultrasound scoring system;
Igg4-related submandibular and lacrimal gland inflammation;
Curative effect evaluation
- From:
China Medical Equipment
2025;22(5):10-15
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the assessment value of ultrasound scoring system combined with shear wave elastography(SWE)on curative effect of IgG4-related submandibular and lacrimal gland inflammation.Methods:This study was a prospective cohort study.A total of 103 patients with IgG4-related submandibular and/or lacrimal gland inflammation who admitted to the Department of Rheumatology and Immunology of Beijing Friendship Hospital,Capital Medical University from September 2022 to December 2024 were consecutively included.They were divided into an effective group(45 cases)and a non-effective group(58 cases)based on the curative effect.All patients were assessed by conventional ultrasound and SWE before and after treatment.Logistic regression analysis was used to determine the independent influencing factors of assessing the curative effect,and then,a receiver operating characteristic(ROC)curve and nomograms were drawn.Results:There were no statistically significant differences in gender and age between the effective group and the non-effective group(P>0.05).The difference between the submandibular and lacrimal gland score,change rate of score,difference of mean Young's modulus(Emean),Emean change rate,difference of maximum value of Young's modulus(Emax),and Emax change rate in the effective group were all higher than those in the non-effective group,and the differences were statistically significant(Z=-7.916,-7.680,-6.767,-6.722,-6.360,-5.957,P<0.05),respectively.The difference between the submandibular and lacrimal gland score(OR=2.90,P<0.001)and the Emax difference(OR=1.18,P<0.05)had diagnostic value for assessing the curative effectiveness.The area under curve(AUC)value,sensitivity,specificity and accuracy of the difference between submandibular and lacrimal gland score were respectively 0.945,88.9%,94.8%and 87.4%in assessing the curative effectiveness.The above indicators of Emax difference were respectively 0.866,86.7%,70.7%and 77.7%in assessing the curative effectiveness.The above indicators of the combination of them were respectively 0.976,93.3%,94.8%and 94.2%.Conclusion:The combination of the conventional ultrasound scoring system and SWE has higher diagnostic value in assessing the curative effect of IgG4-related submandibular and lacrimal gland inflammation.The combined application can significantly improve the accuracy and provide reliable imaging reference for clinical practice.
