Photon-counting detector-CT combined with"four-lows"protocol for coronary CT angiography
10.13929/j.issn.1003-3289.2025.06.027
- VernacularTitle:光子计数探测器CT联合"四低"方案用于冠状动脉CT血管成像
- Author:
Weiting ZHANG
1
;
Kehui NIE
;
Dian YUAN
;
Yicun ZHANG
;
Ke QI
;
Mengyuan ZHANG
;
Yanbo GU
;
Yan CHEN
;
Jianbo GAO
;
Yonggao ZHANG
;
Jie LIU
Author Information
1. 郑州大学第一附属医院放射科,河南郑州 450052
- Publication Type:Journal Article
- Keywords:
coronary artery disease;
angiocardiography;
image quality;
photon-counting detector;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2025;41(6):976-980
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the feasibility of photon-counting detector(PCD)-CT combined with"four-lows"protocol(low contrast agent concentration,low contrast dose,low contrast agent flow rate,low radiation dose)for coronary CT angiography(CCTA).Methods Totally 106 patients with suspected coronary artery disease were prospectively enrolled and randomized into energy-integrating detector(EID)-CCTA(group A,using conventional scanning protocol,n=52)or PCD-CCTA(group B,using"four-lows"scanning protocol,n=54)groups and underwent relative examinations.The radiation dose,subjective and objective evaluation results of imaging quality were compared between groups.Results The contrast agent dose and flow rate,volume CT dose index,dose length product and effective dose in group B were all lower than those in group A(all P<0.001).The subjective scores in group B were higher than in group A(5[4,5]vs.4[4,5],Z=-2.310,P=0.021).Compared with group A,CT value,signal-to-noise ratio and contrast-to-noise ratio of aortic root and most of the main branches of coronary arteries increased in group B,while standard deviation of CT value decreased(all P<0.05).Conclusion PCD-CT combined with"four-lows"protocol could be used for CCTA,which could improve imaging quality and reduce contrast agent usage and radiation dose.