Correlations of multimodal ultrasound manifestations of Hashimoto thyroiditis with normal thyroid function and serum TPOAb titer
10.13929/j.issn.1003-3289.2025.06.011
- VernacularTitle:甲状腺功能正常桥本甲状腺炎多模态超声表现与血清TPOAb滴度的相关性
- Author:
Qiqi WANG
1
;
Wuping ZHANG
;
Zhiguo DING
;
Xin'ai LI
;
Yan YANG
;
Zhaoxin WANG
Author Information
1. 北京中医药大学东方医院功能科,北京 100071;北京中医药大学孙思邈医院超声医学科,陕西铜川 727100
- Publication Type:Journal Article
- Keywords:
thyroiditis;
ultrasonography;
thyroid peroxidase antibody
- From:
Chinese Journal of Medical Imaging Technology
2025;41(6):899-902
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlations of multimodal ultrasound manifestations of Hashimoto thyroiditis(HT)with normal thyroid function and serum thyroid peroxidase antibody(TPOAb)titer.Methods Data of gray-scale ultrasound,CDFI and shear wave elastography(SWE)of 100 HT patients with normal thyroid function were retrospectively analyzed.According to gray-scale ultrasound manifestations,HT was classified into focal type(type A),nodular-like type(type B),diffuse hypoechoic type(type C)and diffuse hyperechoic type(type D).Meanwhile,based on blood flow distribution shown on CDFI,HT was classified into abundant type,increased type,normal type and sparse type.Correlations of the mean Young's modulus(Emean)of thyroid gland and CDFI classification of HT with serum TPOAb titer were analyzed.Results For all 100 cases,serum TPOAb titer was(270.31±72.63)IU/ml.There were 38 cases of type A,26 cases of type B,20 cases of type C and 16 cases of type D based on gray-scale ultrasound,and 15 cases of abundant type,9 cases of increased type,69 cases of normal type and 7 cases of sparse type based on CDFI,respectively.The Emean of thyroid in all 100 cases was(22.31±7.38)kPa.Significant differences of serum TPOAb titer and thyroid Emean were found among different gray-scale ultrasound HT types(all P＜0.05).Thyroid Emean values of all 100 patients were positively correlated with TPOAb titer(rs=0.702,P=0.037).The thyroid Emean of patients with type A,B,C and D HT were positively correlated with TPOAb titer(rs=0.752,0.823,0.853,0.497,all P＜0.05),while the CDFI types of HT were negative correlated with serum TPOAb titer(rs=-0.746,P=0.035).Conclusion Both thyroid Emean and blood flow signals in HT patients with normal thyroid function were correlated with serum TPOAb titer.
