Prenatal ultrasound evaluation on morphology of Sylvian fissure during the second and third trimesters for screening fetal abnormal cerebral cortical development
10.13929/j.issn.1003-3289.2025.06.002
- VernacularTitle:孕中晚期产前超声评估外侧裂形态筛查胎儿大脑皮质发育异常
- Author:
Yayan CHEN
1
;
Hui HUANG
;
Ke WANG
;
Yingni WEI
;
Jiayin LIAO
;
Shengli LI
Author Information
1. 深圳市龙华区妇幼保健院超声科,广东 深圳 518109
- Publication Type:Journal Article
- Keywords:
fetus;
ultrasonography,prenatal;
cerebral cortex;
Sylvian fissure
- From:
Chinese Journal of Medical Imaging Technology
2025;41(6):861-865
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of prenatal ultrasound evaluation on morphology of Sylvian fissure(SF)during the second and third trimesters for screening fetal abnormal cerebral cortical development.Methods Totally 876 fetuses in the second and third trimesters were retrospectively included.Prenatal ultrasound was performed to observe the morphology of fetal SF and whether there was complicated abnormalities of the development of cerebral cortical and other structures.Then prenatal ultrasound was regularly reexamined,and the pregnancy outcome,while the growth and development of newborns were followed up.Results Among 876 fetuses,normal SF morphology was observed in 861 fetuses(861/876,98.29％),while 11 fetuses(11/876,1.26％)had delayed SF development(normal SF morphology but inconsistent with gestational week)and 4 fetuses(4/876,0.46％)had abnormal SF morphology,all complicated with abnormal cerebral cortical development and/or intracranial and extracranial structural malformations,and reexamination of prenatal ultrasound showed that SF morphology was consistent with the gestational week in 4 fetuses,SF morphology still did not match the gestational week in 4 fetuses,and SF morphology was still abnormal in 2 fetuses.Among these 15 fetuses,6 were successfully born and grew well after followed up until 10-15 months,4 were induced labor,while the rest 4(3 with delayed SF development and 1 with abnormal SF morphology)complicated with other severe malformations and 1 with abnormal SF morphology were induced labor or lost to follow-up,hence not undergoing ultrasound re-examination.Conclusion Prenatal ultrasound evaluation on SF morphology during the second and third trimesters had important value for screening fetal abnormal cerebral cortical development.
