Occurrence and influencing factors of multiple organ dysfunction syndrome in elderly patients with subarachnoid hemorrhage
10.3969/j.issn.1009-0126.2025.07.023
- VernacularTitle:老年蛛网膜下腔出血患者多器官功能障碍综合征发生情况及影响因素探讨
- Author:
Xiuqin YANG
1
;
Lingli ZHANG
;
Zhenshen LONG
;
Li ZHANG
;
Xin LIAO
;
Zhongxia LIU
Author Information
1. 556000 凯里,贵州医科大学第二附属医院(黔东南州第二人民医院)神经外科
- Publication Type:Journal Article
- Keywords:
aged;
subarachnoid hemorrhage;
multiple organ failure;
root cause analysis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2025;27(7):941-945
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the occurrence and influencing factors of MODS in elderly pa-tients with SAH.Methods A retrospective analysis was conducted on 187 elderly SAH patients admitted in the Second Affiliated Hospital of Guizhou Medical University from January 2021 to June 2024.According to the presence or absence of MODS,they were divided into MODS group(81 cases)and non-MODS group(106 cases).Their general clinical data were compared between the two groups.Multivariate logistic regression analysis was used to identify the risk factors for MODS in elderly SHA patients.ROC curve analysis was applied to evaluate the predictive value of the major risk factors for MODS in the patients.Results The MODS group had significantly ad-vanced age,larger proportion of modified Fisher grades Ⅲ—Ⅳ,higher APACHE Ⅱ score,and in-creased FPG level than the non-MODS group(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that APACHE Ⅱ score(OR=1.108,95％CI:1.070-1.148,P=0.000)and mo-dified Fisher grade(OR=1.143,95％CI:1.095-1.194,P=0.000)were independent risk factors for MODS in elderly SAH patients.ROC curve analysis suggested that the AUC value of APACHE Ⅱ score,modified Fisher grade and their combination in predicting the occurrence of MODS in elderly SAH patients was 0.809,0.737 and 0.880,respectively,with a sensitivity of 59.35％,88.93％and 84.02％,and a specificity of 88.73％,58.52％and 81.15％,respectively.The combined detection showed better predictive performance than the indicator alone(P＜0.01).Con-clusion The incidence of MODS is quite high in elderly patients with SAH.APACHE Ⅱ score and modified Fisher grade are the main risk factors affecting the occurrence of MODS.
