Research progress on pathogenesis of swine enteric coronaviruses
10.16303/j.cnki.1005-4545.2024.12.24
- VernacularTitle:猪肠道冠状病毒的致病机制研究进展
- Author:
Jiulong GU
1
;
Shilei HUANG
1
;
Yanling YIN
1
Author Information
1. 重庆三峡职业学院动物科技学院,重庆万州 404155
- Publication Type:Journal Article
- Keywords:
swine enteric coronaviruses;
pathogenesis;
invasion mechanisms;
immune evasion
- From:
Chinese Journal of Veterinary Science
2024;44(12):2667-2672
- CountryChina
- Language:Chinese
-
Abstract:
Swine enteric coronaviruses(SeCoVs),including transmissible gastroenteritis virus(TGEV),porcine epidemic diarrhea virus(PEDV),porcine deltacoronavirus(PDCoV)and swine acute diarrhea syndrome coronavirus(SADS-CoV),are common pathogens that cause acute lethal diarrhea in neonatal piglets.TGEV and PEDV have been circulating among swine for decades with-out effective control.The recent emergence of PDCoV and SADS-CoV are not only highly patho-genic to neonatal piglets,but also pose a risk of cross-species transmission.Despite the availability of many commercial vaccines against TGEV and PEDV,they remain widespread,and there are cur-rently no vaccines available for PDCoV and SADS-CoV.Therefore,it is crucial to elucidate the pathogenesis of SeCoVs.This review describes recent developments in the invasion and immune e-vasion mechanisms of SeCoVs,and attempts to provide references for prevention and control of SeCoVs.
