Evaluation of endometrial receptivity in infertile patients using multimodal ultrasound combined with sex hormone detection
10.3969/j.issn.1673-9701.2025.07.006
- VernacularTitle:多模态超声联合性激素检测对不孕患者子宫内膜容受性的评估
- Author:
Yanhua DING
1
;
Jiqin YAO
;
Zhenyun LIN
;
Xiaoling ZHU
;
Xiaoqing ZHU
Author Information
1. 杭州市妇产科医院超声科,浙江 杭州 310008
- Publication Type:Journal Article
- Keywords:
Endometrial receptivity;
Multimodal ultrasound;
Sex hormones;
Luteinizing hormone;
Estradiol;
Progesterone
- From:
China Modern Doctor
2025;63(7):24-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of multimodal ultrasound combined with sex hormone detection in evaluating endometrial receptivity in infertile patients.Methods Ninety-five infertile patients who received in vitro fertilization and embryo transfer treatment in Hangzhou Women's Hospital from January 2020 to February 2023 were selected as study objects,and they were divided into pregnant group(55 cases)and non-pregnant group(40 cases)according to the pregnancy status of the first embryo transfer.Sex hormone levels and multimodal ultrasound scores were compared between two groups,and receiver operating characteristic(ROC)curve was drawn to evaluate the value of each indicator in predicting pregnancy of infertile patients individually and in combination.Results The endometrial thickness score,endometrial volume score,vascular blood flow score and multimodal ultrasound score of pregnant group were significantly higher than those of non-pregnant group(P＜0.05).The levels of luteinizing hormone(LH),estradiol(E2)and progesterone(P)in pregnant group were significantly higher than those in non-pregnant group(P＜0.05).ROC curve results showed that the area under the curve(AUC)of LH,E2 and multimodal ultrasound scores in predicting pregnancy in infertile patients were all＞0.7,which had certain predictive value,and the three indicators combined with P had the highest predictive value,with an AUC of 0.889.Conclusion The combination of multimodal ultrasound and sex hormone detection can effectively evaluate the endometrial receptivity of infertile patients,and has certain reference value for predicting the pregnancy status of infertile patients.
