Analysis of adverse pregnancy outcomes in fetuses with thickening of the nuchal translucency
10.3969/j.issn.1673-9701.2025.17.001
- VernacularTitle:颈项透明层增厚胎儿不良妊娠结局分析
- Author:
Yameng REN
1
;
Maohuan BAI
1
;
Xuezhe OUYANG
1
;
Mengru WANG
1
;
Xiao HAN
1
;
Xiaotian CHEN
1
;
Mengdie ZHANG
1
;
Ling LIU
1
Author Information
1. 郑州大学第三附属医院产前诊断科,河南郑州 450052
- Publication Type:Journal Article
- Keywords:
Nuchal translucency;
Prenatal diagnosis;
Structural malformations;
Pregnancy outcome
- From:
China Modern Doctor
2025;63(17):1-3,24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the adverse pregnancy outcomes of fetuses with increased nuchal translucency(NT).Methods A total of 376 pregnant women at the Third Affiliated Hospital of Zhengzhou University from May 2023 to January 2024 were selected as research subjects,who had a diagnosis of fetal NT ≥ the 95th percentile and complete pregnancy outcomes for singleton pregnancies.The fetuses were divided into simple thickening group(n=320)and thickening with structural abnormalities group(n=56)based on NT ultrasound results.The interventional prenatal diagnosis outcomes and pregnancy outcomes of two groups were compared.Results The rate of chromosomal abnormalities and the incidence of adverse pregnancy outcomes were higher in thickening with structural abnormalities group compared to simple thickening group with statistically significant differences(P＜0.05).The overall incidence of adverse pregnancy outcomes in NT thickened fetuses was 31.65％,but after excluding chromosomal abnormalities and structural malformations,the good pregnancy outcome rate in NT thickened fetuses was 98.09％.Conclusion NT thickening is associated with adverse pregnancy outcomes in fetuses,and the risk of poor fetal outcome is further increased when NT thickening combined with structural abnormalities in early pregnancy,but the pregnancy outcome is better in fetuses with NT thickening after excluding chromosomal abnormalities and structural malformations.
