Analysis of the curative efficacy and safety of ultrasound-guided MWA combined with PEI in treating thyroid cystic solid nodule
10.3969/j.issn.1672-8270.2025.04.017
- VernacularTitle:超声引导下微波消融联合无水乙醇消融治疗甲状腺囊实性结节的疗效及安全性分析
- Author:
Fan ZHOU
1
;
Shaohong ZHANG
;
Changsong XU
;
Zhengqing MU
;
Jun LU
Author Information
1. 南京医科大学附属淮安第一医院超声科 淮安 223300
- Publication Type:Journal Article
- Keywords:
Thyroid nodule;
Microwave ablation(MWA);
Percutaneous ethanol injection(PEI);
Ultrasound-guided;
Safety
- From:
China Medical Equipment
2025;22(4):84-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the curative efficacy and safety of microwave ablation(MWA)combined with percutaneous ethanol injection(PEI)in treating thyroid cystic solid nodule.Methods:A total of 62 patients with thyroid cystic solid nodule,who admitted to The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University from January 2021 to December 2022,were selected,and they were divided into microwave group(n=28,only single MWA)and combination group(n=34,MWA combined with PEI)according to different treatment plans.The reduction rate of the volume of thyroid nodules,indicators of thyroid function,clinical symptom and the score of physical signs,as well as the incidence of perioperative complications,were compared between two groups after treatment.Results:After treatment,the reduction rate of the volume of thyroid nodule was(88.97±6.36)%in the combination group,which was higher than that(88.15±5.69)%in the microwave group,and the differences in those indicators between the two groups were statistically significant(t=2.465,P<0.05).The differences of the indicators of thyroid function before and after treatment between two groups were not significant(P>0.05).The clinical symptoms and the scores of physical signs of both groups after treatment were lower than that before treatment(P>0.05).The incidence of perioperative complications in the combination group was 17.65%,which was lower than 42.68%in the microwave group(P<0.05),and the difference of that between the two groups was significant(x2=4.736,P<0.05).Conclusion:The curative efficacy of the combination of MWA and PEI is better than MWA alone,which has better safety.