A study on the safety and efficacy of transesophageal echocardiography-guided percutaneous patent foramen ovale closure for the treatment of migraine
10.3969/j.issn.1672-8270.2025.04.013
- VernacularTitle:经食管超声心动图引导下经皮卵圆孔未闭封堵术治疗偏头痛安全性和有效性研究
- Author:
Lijun ZHOU
1
;
Jian WANG
1
;
Bei CHEN
1
;
Juan DAI
1
;
Hongmei YE
1
Author Information
1. 绵阳市第三人民医院超声科 绵阳 621000
- Publication Type:Journal Article
- Keywords:
Patent foramen ovale;
Transesophageal echocardiography;
Intervention;
Closure
- From:
China Medical Equipment
2025;22(4):64-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the safety and efficacy of transesophageal echocardiography(TEE)-guided percutaneous patent foramen ovale(PFO)closure in treating migraine.Methods:A total of 78 patients with migraine who underwent TEE-guided percutaneous PFO closure at The Third Hospital of Mianyang between March 2021 and August 2023 were included in the study.The impact of headache on daily life was assessed using the Headache Impact Test(HIT-6)score.Preoperatively conventional examination included TEE,right heart acoustic imaging,and contrast transcranial Doppler(c-TCD)were conducted to assess the situation of foramen ovale and right-to-left shunt(RLS).PFO closure was completed under TEE monitoring in surgery,and TEE examination was immediately implemented after surgery so as to evaluate the effect of closure.The transthoracic TTE,right heart acoustic imaging and c-TCD were adopted to conduct follow-up for the form and position of occluder,and the situation of residual shunt at the 1st,3rd and 6th month after surgery.HIT-6 score was used to assess whether the headache of patients was improved.Results:Transesophageal echocardiography(TEE)-guided PFO closure was successfully performed in 75 patients(success rate was 96%),while 3 cases was failure in closure.There was not major surgical complications in all patients.During follow-up,TTE demonstrated the position and form of occluder were well,and there was not pericardial effusion.The results of right heart acoustic imaging and c-TCD showed the RLS obviously reduced or even disappeared after closure.HIT-6 scores showed the number of patients,whose scores were less than 50 scores,increased at the 1st,3rd and 6th after closure,which were respectively 44 cases,49 cases and 64 cases,and the differences of them were significant(x2=49.912,82.041,96.189,P＜0.05).Conclusion:The single TEE-guided percutaneous PFO closure is safe,which short-term outcomes is favorable for migraine.This technique is worth in clinical application.
