Research progress of microfibril-associated protein 2 in malignant tumors
10.3760/cma.j.cn113884-20241009-00295
- VernacularTitle:微原纤维相关蛋白2在恶性肿瘤中的研究进展
- Author:
Zhijie DING
1
;
Weiming YANG
;
Yong YAN
;
Miaokang XU
;
Minglong HUANG
;
Hao WANG
;
Yongping ZHOU
Author Information
1. 南京医科大学附属无锡第二医院肝胆外科，无锡 214002
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Prognosis;
Microfibrillar-associated protein 2;
Therapeutic target
- From:
Chinese Journal of Hepatobiliary Surgery
2025;31(7):557-560
- CountryChina
- Language:Chinese
-
Abstract:
Microfibrino-associated protein (MFAP) 2 is an extracellular matrix glycoprotein and a member of the MFAP family. It participates in the assembly of extracellular elastic microfibers.Upregulation of MFAP2 can promote the occurrence and development of various tumors and regulate multiple cancer-related signaling pathways and is related to their prognosis, making it a potential target for tumor treatment. This article summarizes the research progress on the pathogenesis, targeted therapy and prognosis of MFAP2 in malignant tumors.
