Research progress of intermittent fasting in treatment of multiple sclerosis
10.3969/j.issn.1000-484X.2025.01.033
- VernacularTitle:间歇性禁食治疗多发性硬化的研究进展
- Author:
Weili GUO
1
;
Miao LI
1
;
Jin LI
1
;
Di PAN
1
;
Xiyan KUANG
1
;
Dan YANG
1
Author Information
1. 哈尔滨医科大学附属第二医院神经内科,哈尔滨 150081
- Publication Type:Journal Article
- Keywords:
Intermittent fasting;
Multiple sclerosis;
Experimental allergic encephalomyelitis
- From:
Chinese Journal of Immunology
2025;41(1):216-219,225
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis(MS)is a chronic central nervous system inflammatory demyelinating disease caused by autoim-mune diseases.Intermittent fasting(IF)is a dietary pattern with periodic energy limitation.Studies have shown that IF can delay the occurrence and development of MS and experimental allergic encephalomyelitis(EAE).Its mechanism of action includes repairing nerve damage,promoting myelin regeneration,regulating gut microbiota,and reversing immune inflammation.The use of IF can re-duce the severity,recurrence time,and lesion size of MS patients clinically,which brings new ideas for the treatment and prevention of MS.This article provides a review of the effects and mechanisms of IF in treating MS,with the aim of gaining new insights into the treatment of MS and providing reference for the application of IF in the treatment of MS patients.
