Lactoferrin:Potential as a cancer therapeutic agent and anticancer drug delivery system
10.3969/j.issn.1000-484X.2025.01.032
- VernacularTitle:乳铁蛋白:作为癌症治疗剂与抗癌药物递送系统的潜力
- Author:
Jinxian SU
1
;
Xiaomei MA
;
Xingfu SHU
;
Yao CHEN
;
Haixia ZHANG
;
Jialin BAI
Author Information
1. 西北民族大学生物医学研究中心生物工程与技术国家民委重点实验室,兰州 730030;西北民族大学生命科学与工程学院,兰州 730030
- Publication Type:Journal Article
- Keywords:
Lactoferrin;
Antitumor effect;
Drug carrier
- From:
Chinese Journal of Immunology
2025;41(1):209-215
- CountryChina
- Language:Chinese
-
Abstract:
At present,malignant tumor diseases occur frequently and increase year by year.Traditional chemoradiotherapy methods are expensive,have serious toxic and side effects,and are easy to reduce patient tolerance.Natural medicines have advantages of multiple targets,high selectivity and low toxicity and side effects in process of anti-tumor,and are one of important sources of anti-tumor drugs.As a polypeptide substance,lactoferrin has a strong anti-tumor effect and plays a huge role in field of nano-drug delivery.Receptors of lactoferrin are widely expressed on surface of various cancer cells.In addition to its strong anti-tumor effect,it is also widely used to modify nanocarriers.In this paper,anti-tumor mechanism of lactoferrin is reviewed,and the latest research progress of using lactoferrin as an anti-cancer drug delivery carrier is also introduced.
