Translation of the Quality of Life Tool for Patients with Aplastic Anaemia and the test of its reliability and validity
10.3760/cma.j.cn211501-20240401-00755
- VernacularTitle:再生障碍性贫血患者生命质量量表的汉化及信效度检验
- Author:
Yu ZHANG
1
;
Jinsong YAN
;
Ding DING
;
Zhijie KANG
;
Xiaotong GUO
;
Yue WEI
;
Yingying REN
;
Junfeng CHEN
Author Information
1. 大连医科大学公共卫生学院,大连 116044
- Publication Type:Journal Article
- Keywords:
Aplastic anemia;
Quality of life;
Scale;
Reliability and validity
- From:
Chinese Journal of Practical Nursing
2025;41(2):135-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To translate the quality of life tool for patients with aplastic anaemia and paroxysmal nocturnal haemoglobinuria (QLQ-AA/PNH) into Chinese, and to test its reliability and validity.Methods:According to the scale translation principle, the Chinese version of QLQ-AA/PNH was formed through translation, back translation and cross-cultural adaptation. A cross-sectional survey method was used to conveniently select 58 patients with aplastic anemia who were treated in the hematology department of the Second Affiliated Hospital of Dalian Medical University from January 2018 to September 2023 for investigation, and to evaluate the reliability and validity of the scale.Results:The Chinese version of QLQ-AA/PNH retains 36 items, and 5 common factors (psychological status dimension, life burden dimension, physical condition dimension, illness anxiety dimension and other symptom dimension) were extracted through exploratory factor analysis. The cumulative variance contribution rate reached 71.33%, and the factor load of each entry was greater than 0.5 on corresponding common factors. The Cronbach α coefficient of the scale as a whole was 0.971, the broken half reliability coefficient was 0.985, the Cronbach α coefficient of each common factor was 0.637 to 0.954, and the broken half reliability coefficient was 0.637 to 0.930. Conclusions:The Chinese version of QLQ-AA/PNH has been proved to be valid and reliable. It is a valuable tool for evaluating the quality of life among patients with aplastic anaemia.