Clinical effects of Jiawei Yanghe Decoction combined with Budesonide and Formoterol Fumarate Powder for Inhalation on patients with mild to moderate bronchial asthma in chronic and persistent period
10.3969/j.issn.1001-1528.2025.01.012
- VernacularTitle:加味阳和汤联合布地奈德福莫特罗粉吸入剂对轻中度慢性持续期支气管哮喘患者的临床疗效
- Author:
Yu WANG
1
;
Hui-yong ZHANG
;
Lin-jin CHEN
;
Zheng-yi ZHANG
;
Cui LI
;
Jie CUI
;
Ben SU
;
Ping BAI
;
Zi-feng MA
;
Zhen-hui LU
Author Information
1. 上海中医药大学附属龙华医院,上海 200032
- Publication Type:Journal Article
- Keywords:
Jiawei Yanghe Decoction;
Budesonide and Formoterol Fumarate Powder for Inhalation;
mild to moderate bronchial asthma;
chronic and persistent period;
pulmonary functions;
airway inflammatory reactions
- From:
Chinese Traditional Patent Medicine
2025;47(1):81-86
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Jiawei Yanghe Decoction combined with Budesonide and Formoterol Fumarate Powder for Inhalation on patients with mild to moderate bronchial asthma in chronic and persistent period.METHODS One hundred and eighteen patients were randomly assigned into control group(59 cases)for 4-week administration of Budesonide and Formoterol Fumarate Powder for Inhalation,and observation group(59 cases)for 4-week administration of both Jiawei Yanghe Decoction and Budesonide and Formoterol Fumarate Powder for Inhalation.The changes in clinical effects,ACT score,bronchial asthma control rate,pulmonary function indices(FEV1,PEF,FEV1％,PEF％),inflammatory indices(EOS,EOS％,FeNO),TCM syndrome score and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed increased bronchial asthma control rate,ACT score,PEF(P＜0.05),and decreased TCM syndrome score(P＜0.05),especially for the observation group(P＜0.05);the observation group exhibited increased FEV1,FEV1％,PEF％(P＜0.05),among which FEV1,PEF％were higher than those in the control group(P＜0.05);the observation group showed decreased inflammatory indices(P＜0.05),among which FeNO was lower than that in the control group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with mild to moderate bronchial asthma in chronic and persistent period,Jiawei Yanghe Decoction combined with Budesonide and Formoterol Fumarate Powder for Inhalation can safely and effectively alleviate clinical symptoms,improve pulmonary functions,airway inflammatory reactions,and enhance bronchial asthma control rate.
