Efficacy of laparoscopic salpingectomy in the treatment of ectopic pregnancy in patients and its effects on serum human chorionic gonadotropin levels
10.3760/cma.j.cn341190-20250103-00014
- VernacularTitle:LSAS治疗异位妊娠的效果观察及对患者血清hCG水平的影响
- Author:
Xue LENG
1
;
Xiuping WANG
1
Author Information
1. 建德市妇幼保健院妇产科，建德 311600
- Publication Type:Journal Article
- Keywords:
Pregnancy, ectopic;
Salpingectomy;
Laparoscopy;
Chorionic gonadotropin;
Abdominal pain;
Postoperative complications
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(10):1446-1449
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of laparoscopic salpingectomy in the treatment of ectopic pregnancy in patients and its effects on serum human chorionic gonadotropin levels.Methods:This study used a case-control design. A retrospective analysis was conducted on 70 patients with ectopic pregnancy who received treatment at Jiande Maternal and Child Health Care Hospital from January 2021 to December 2023. The patients were divided into a control group and an observation group ( n =35/group) according to the surgical methods used. The control group underwent open surgery, while the observation group received laparoscopic salpingectomy. Clinical indicators, postoperative recovery metrics, complications, and the time taken for symptom resolution were compared between the two groups. Serum human chorionic gonadotropin levels were measured and compared between the two groups both before surgery and 1 week after surgery. Results:The operation time in the observation group was longer than that in the control group [(45.87 ± 7.28) minutes vs. (36.52 ± 5.61) minutes, t = 6.02, P<0.001]. The intraoperative blood loss in the observation group was significantly less than that in the control group [(45.39 ± 8.84) mL vs. (93.42 ± 14.36) mL, t = -16.85, P<0.001]. The time to first passage of flatus, time to ambulation, and length of hospital stay in the observation group were (13.43 ± 3.61) hours, (6.98 ± 1.43) hours, and (4.01 ± 1.23) days, respectively, which were significantly shorter than those in the control group [(21.29 ± 4.57) hours, (11.29 ± 2.75) hours, (6.72 ± 1.84) days, t = -7.98, -8.23, -7.24, all P<0.001]. The incidence of complications in the observation group was significantly lower than that in the control group [8.57% (1/35) vs. 31.43% (8/35), χ2 = 4.59, P = 0.017]. The time to pain resolution, time to disappearance of vaginal bleeding, and the time for menstrual recovery in the observation group were (3.56 ± 0.75) days, (7.68 ± 1.37) days, and (30.04 ± 8.73) days, respectively, which were significantly shorter than those in the control group [(4.90 ± 1.34) days, (9.74 ± 1.52) days, (46.58 ± 12.31) days, t = -5.16, -5.96, -7.24, all P<0.001]. At 1 week after surgery, serum human chorionic gonadotropin levels in the observation group were significantly lower than those in the control group [(315.24 ± 39.48) IU/L vs. (559.71 ± 45.62) IU/L, t = -23.97, P<0.001]. Conclusions:Laparoscopic salpingectomy is highly effective for treating ectopic pregnancy. It can accelerate postoperative recovery and reduce serum human chorionic gonadotropin levels.
