Prognostic value of pSOFA score combined with AGI grade in children with sepsis
10.3969/j.issn.1673-9701.2025.02.014
- VernacularTitle:pSOFA评分联合AGI分级评估脓毒症患儿预后的价值
- Author:
Xinyang QIAN
1
;
Yumin WANG
Author Information
1. 包头医学院研究生院,内蒙古包头 014040
- Publication Type:Journal Article
- Keywords:
Pediatrics;
Sepsis;
Acute gastrointestinal injury
- From:
China Modern Doctor
2025;63(2):54-57
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognostic factors of acute gastrointestinal injury(AGI)in children with sepsis,and to explore the predictive value of pediatric sequential organ failure assessment(pSOFA)score,AGI grade and their combined for prognosis.Methods A total of 143 children with sepsis complicated with AGI in Inner Mongolia Maternal and Child Health Hospital from January 2020 to January 2022 were selected and divided into sepsis group(n=1 03)and septic shock group(n=40)according to the severity of disease.pSOFA score was obtained on the day when sepsis was diagnosed.AGI was evaluated every day during hospitalization.Multivariate Logistic regression was used to identify independent factors affecting the outcome.Receiver operating characteristic(ROC)curve was used to analyze predictive value of pSOFA score,AGI grade and their combination for poor prognosis.Results The number of patients who received continuous renal replacement therapy,surgery,mechanical ventilation,bloody stool,hypoactive bowel sound and procalcitonin concentration in septic shock group were higher than those in sepsis group(P＜0.05).Red blood cell,hemoglobin and platelet in septic shock group were lower than those in sepsis group(P＜0.05).Multivariate Logistic regression analysis showed that mechanical ventilation,surgery,decrease of hemoglobin,increase of pSOFA score and AGI grade were independent risk factors for poor prognosis in patients(P＜0.05).ROC curve analysis showed that predictive value of pSOFA score combined with AGI grading for prognosis of patients was higher than that of them alone(P＜0.05).Conclusion Mechanical ventilation,surgery,hemoglobin,pSOFA score and AGI grade are prognostic factors of sepsis complicated with AGI in children.pSOFA score combined with AGI grade has a high value in predicting poor prognosis.
