Impact of physical functioning on supportive care needs in patients with hepatocellular carcinoma: a chain-mediated model involving perceived social support, anxiety, and depression
10.3760/cma.j.cn211501-20250612-01769
- VernacularTitle:原发性肝癌患者身体功能状态对支持性照护需求的影响：领悟社会支持与焦虑抑郁的链式中介作用
- Author:
Lanfang ZHUO
1
;
Yu WANG
;
Quan JIANG
;
Xiaolong CHEN
;
Xiaolan WANG
;
Yanhua SHI
;
Xianmei MENG
Author Information
1. 暨南大学附属第一医院肝胆外科，广州 510630
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Social support;
Anxiety;
Depression;
Physical function status;
Supportive care needs;
Chain mediation effect
- From:
Chinese Journal of Practical Nursing
2025;41(34):2646-2654
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the influence of physical function status on supportive care needs (SCNS) in patients with primary liver cancer (PLC) and to explore the mediating roles of perceived social support and anxiety-depression, with the aim of providing evidence for nursing interventions to improve patients' care experience.Methods:A convenience sampling method was used to select PLC inpatients admitted to The First Affiliated Hospital of Jinan University between December 2022 and February 2024. Data were collected using a general information questionnaire, the 34-item Supportive Care Needs Survey-Short Form, the Hospital Anxiety and Depression Scale, the Perceived Social Support Scale, and the Karnofsky Performance Status Scale to conduct a cross-sectional survey. Pearson correlation analysis was performed to examine associations among SCNS, perceived social support, anxiety-depression, and physical function status. Structural equation modeling was used to assess the mediating effects of perceived social support and anxiety-depression on the relationship between physical function status and SCNS.Results:A total of 304 patients were enrolled, including 260 males and 44 females, 31 cases aged 18-40 years old, 160 cases aged 41 to 60 years old, and 113 cases over 60 years old. The mean total SCNS score was (98.32 ± 21.75) points, the mean anxiety-depression score was (23.31 ± 9.64) points, the mean perceived social support score was (56.62 ± 13.05) points, and the mean physical function status score was (66.28 ± 12.31) points. Pearson correlation analysis showed that physical function status was negatively correlated with SCNS and anxiety-depression ( r =-0.509, -0.447; both P<0.05) and positively correlated with perceived social support ( r =0.439, P<0.05). Physical function status had a direct effect of 60.74% on SCNS, with specific mediating effects of perceived social support and anxiety-depression accounting for 23.15% and 11.85%, respectively, and a chain mediating effect of 4.26%. Conclusions:Patients with PLC exhibited a moderately high level of supportive care needs. Physical function status not only exerted a direct negative effect on SCNS but also indirectly influenced SCNS through the chain mediation of perceived social support and anxiety-depression. Clinical medical staff should focus on enhancing patients' perception of social support and effectively alleviating anxiety and depressive symptoms, thereby reducing supportive care needs to some extent.
