MR vessel wall imaging for predicting instability status of intracranial aneurysm
10.13929/j.issn.1003-3289.2025.01.004
- VernacularTitle:基于MR血管壁成像预测颅内动脉瘤不稳定状态
- Author:
Xinmei MA
1
;
Qichang FU
;
Shanshan XIE
;
Yong ZHANG
;
Jingliang CHENG
;
Sheng GUAN
Author Information
1. 郑州大学第一附属医院磁共振科,河南郑州 450052
- Publication Type:Journal Article
- Keywords:
intracranial aneurysm;
vessel wall;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):15-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of MR vessel wall imaging(VMI)for predicting instability status of intracranial aneurysm(IA).Methods MR angiography(MRA)and vascular wall imaging(VWI)data of 506 patients with single IA were retrospectively analyzed.Asymptomatic IA was included in stable status group(n=349),while those with enlargement during follow-up or threatened rupture symptoms were taken as instable status group(n=157).The patients were divided into training set(n=354)and validation set(n=152)at a ratio of 7:3.The least absolute shrinkage and selection operator(LASSO)and multivariate logistic regression were performed to screen risk factors associated with IA instability based on clinical data,MRA and VWI manifestations.Then model 1 was constructed based the above indexes,while model 2 was established based only on MRA manifestations of IA.The receiver operating characteristic curve was plotted,and the area under the curve(AUC)was calculated to evaluate the efficacy of each model for predicting IA instability.Results LASSO and multivariate logistic regression showed that female patient,age＜50 years with history of cerebral infarction and IA wall enhancement on MRA were all independent predictors of IA instability status.The AUC of model 1 for predicting instability status of IA was 0.733 and 0.742 in training set and validation set,respectively,both higher than that of model 2(0.593 and 0.609,both P＜0.05).Conclusion MR VWI was helpful for predicting IA instability status.
