Ultrasonic parameters of diaphragm motion combined with BODE index for predicting acute exacerbation of chronic obstructive pulmonary disease
10.13929/j.issn.1003-3289.2025.01.019
- VernacularTitle:超声测量膈肌运动参数联合BODE指数预测慢性阻塞性肺疾病急性加重
- Author:
Fangxin LIU
1
;
Yongfeng REN
;
Jian LI
;
Shanshan WANG
;
Lifang CAO
;
Zhaojie CHEN
Author Information
1. 安徽医科大学附属亳州医院亳州市人民医院超声科,安徽亳州 236800
- Publication Type:Journal Article
- Keywords:
pulmonary disease,chronic obstructive;
diaphragm;
ultrasonography;
respiratory function tests
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):90-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of ultrasonic parameters of diaphragm motion combined with BODE index for predicting acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods Eighty COPD patients were retrospectively collected and divided into stable group(n=45)and acute exacerbation group(n=35).Ultrasonic parameters of diaphragm motion,including diaphragm excursion(DE)under quiet breathing(QB)and deep breathing(DB),i.e.DEQB and DEDB were measured.The general data,ultrasound parameters of diaphragm motion,and BODE index scores were compared between groups.Then logistic regression analysis was used to identify factors which could be used to independently predict acute exacerbations of COPD.The predicting performance of ultrasound parameters of diaphragm motion,BODE index and their combination were evaluated with receiver operating characteristic(ROC)curve and the area under the curve(AUC).Results Compared with stable COPD group,acute exacerbation group had higher BMI and BODE index scores(both P＜0.05),as well as larger DEQB but smaller DEDB(both P＜0.05).DEDB and BODE index were both independent predicting factors of acute exacerbation of COPD,while increased DEDB indicated decreased risk of acute exacerbation(OR[95％CI]=0.673[0.493,0.918],P＜0.05),whereas increased BODE index suggested higher risk(OR[95％CI]=3.678[1.061,12.746],P＜0.05).AUC for DEDB and BODE index alone for predicting acute exacerbation of COPD was 0.788 and 0.799,respectively,and of their combination was 0.979,significant higher than that of each alone(both P＜0.05).Conclusion Ultrasonic parameters of diaphragm motion could be used to evaluate diaphragm function in COPD patients.Combination of DEDB and BODE index had better performances in predicting acute exacerbation of COPD.
