Clinical efficacy of cognitive therapy combined with transcranial direct current stimulation in the treatment of schizophrenia
10.3760/cma.j.cn341190-20240406-00344
- VernacularTitle:认知疗法联合经颅直流电刺激治疗精神分裂症效果观察
- Author:
Fuyang YAN
1
;
Lehong XIA
1
;
Chengrong DU
1
Author Information
1. 丽水市第二人民医院精神科，丽水 323000
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Cognitive therapy;
Transcranial direct current stimulation;
Cognition;
Signs and symptoms;
Social behavior
- From:
Chinese Journal of Primary Medicine and Pharmacy
2025;32(5):652-656
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical efficacy of cognitive therapy combined with transcranial direct current stimulation in the treatment of schizophrenia.Methods:A randomized controlled study was conducted involving 118 patients with schizophrenia treated at The Second People's Hospital of Lishui from January 2021 to January 2023. The participants were divided into a control group and an observation group, with 59 patients in each group using a random number table method. The control group received cognitive therapy, while the observation group received cognitive therapy combined with transcranial direct current stimulation. Both groups underwent treatment for 8 weeks. Clinical symptom scores, treatment compliance, and the scores of Excited Component of the Positive and Negative Syndrome Scale, the Berkeley Expressivity Questionnaire, the Insight and Treatment Attitudes Questionnaire, and the Social Behavior Scale were compared between the two groups.Results:After intervention, the scores for activation, cognitive impairment, paranoia, depression, and aggression on the clinical symptom rating scale in the observation group were significantly lower than those in the control group ( t = 8.45, 6.68, 4.60, 6.92, 5.59, all P < 0.001). The overall compliance rate in the observation group was significantly higher than that in the control group [89.8% (53/59) vs. 74.6% (44/59), χ2 = 4.69, P < 0.05]. The score of Excited Component of the Positive and Negative Syndrome Scale in the observation group was significantly lower than that in the control group [(7.92 ± 1.75) vs. (9.35 ± 1.89), t = 4.26, P < 0.001]. The score of the Berkeley Expressivity Questionnaire in the observation group was significantly higher than that in the control group [(61.23 ± 5.79) vs. (55.38 ± 6.05), t = 5.37, P < 0.001]. The score of Insight and Treatment Attitudes Questionnaire in the observation group was significantly higher than that in the control group [(18.74 ± 3.69) vs. (12.41 ± 2.25), t = 11.25, P < 0.001]. The score of the Social Behavior Scale in the observation group was significantly lower than that in the control group [(15.23 ± 3.76) vs. (18.09 ± 4.28), t = 3.86, P < 0.001]. Conclusions:Cognitive therapy combined with transcranial direct current stimulation has shown significant effects in treating patients with schizophrenia. This combination therapy effectively improves treatment compliance and emotional expression abilities, alleviates symptoms of agitation, and enhances cognitive function and social skills in patients.
