High-resolution MR vascular wall imaging for differentiating perforating branch subtype and other subtype basilar artery ischemic stroke
10.13929/j.issn.1003-3289.2025.01.011
- VernacularTitle:高分辨MR血管壁成像鉴别穿支型与其他亚型基底动脉缺血性脑卒中
- Author:
Dan LUO
1
;
Zhongliang RAO
;
Xinlan XIAO
Author Information
1. 南昌大学第二附属医院医学影像中心,江西南昌 330006;智能医学影像江西省重点实验室,江西南昌 330006
- Publication Type:Journal Article
- Keywords:
stroke;
basilar artery;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(1):50-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of high-resolution vascular wall imaging(HR-VWI)for differentiating perforating branch subtype and other subtype basilar artery(BA)ischemic stroke.Methods Totally 147 patients with posterior circulation ischemic stroke were retrospectively enrolled and divided into perforating branch group(perforating branch BA atherosclerosis,n=57)and multi-mechanism group(artery-to-artery embolism and/or hypoperfusion,n=90)according to MRI findings and Chinese ischemic stroke subclassification(CISS).Clinical data,HR-VWI and MR angiography parameters were compared between groups,and those being significantly different were included in logistic regression analysis to construct a model.Receiver operating characteristic curve was drawn,and the area under the curve(AUC)was calculated to evaluate the efficacy of the model for differentiating perforating branch subtype and other subtype BA ischemic stroke.Results The proportion of diabetes mellitus(DM)and dorsal plaque were both higher,while proportion of ventral plaque in perforating branch group was lower than those in multi-mechanism group(all P＜0.05).No significant difference of the other clinical data,nor of the maximum wall thickness,lumen eccentricity index,lumen area,wall area,vascular stenosis rate,plaque load,vascular remodeling index and BA course of culprit plaques section was found between groups(all P＞0.05).DM and dorsal plaque were both independent risk factors for perforating BA atherosclerosis,whereas ventral plaque was the independent protective factor(all P＜0.05).The sensitivity,specificity and AUC of the model for differentiating perforating branch subtype and other subtypes of BA ischemic stroke was 82.46％,70.00％and 0.839,respectively.Conclusion HR-VWI could be used to differentiating perforating branch subtype and other subtype BA ischemic stroke.
