Research progress in diagnosis and treatment strategies of drug-induced liver injury
10.3760/cma.j.cn114015-20220119-00063
- VernacularTitle:药物性肝损伤诊断与治疗研究进展
- Author:
Yifan XU
1
;
Huichun XING
1
Author Information
1. 首都医科大学附属北京地坛医院肝病三科，北京 100015
- Publication Type:Journal Article
- Keywords:
Chemical and drug induced liver injury;
Diagnosis;
Therapeutics
- From:
Adverse Drug Reactions Journal
2022;24(5):258-263
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced liver injury (DILI) is caused by the direct toxicity of drugs and/or their metabolites or the body-specific heterogeneous response to drugs. Since 2019, the European Association for the Study of the Liver, the American College of Gastroenterology, and the Asia Pacific Association of Study of Liver have successively updated previously published guidelines on DILI. Based on the above 3 updated guidelines and in combination with Chinese Diagnosis and Treatment Guideline on Drug-Induced Liver Injury, the Guideline for Primary Care of Drug-Induced Liver Injury (2019), and the relevant literature at home and abroad in recent years, we review the progress on the diagnosis and treatment of DILI in this paper, aiming to help the diagnosis and treatment of DILI in clinic.
