Clinical efficacy and influencing factors of hyperbaric oxygen therapy for spine and spinal cord injury
10.3760/cma.j.cn311847-20200512-00196
- VernacularTitle:脊柱伴脊髓损伤高压氧治疗的临床疗效及影响因素分析
- Author:
Yuji LI
1
;
Nengneng TANG
Author Information
1. 745000 甘肃省庆阳，庆阳市人民医院骨一科
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Spine and spinal cord injury;
Neurological function;
Influencing factors
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2020;27(5):535-538
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy and influencing factors of hyperbaric oxygen (HBO) in the treatment of spine and spinal cord injuries.Methods:A total of 150 patients with spinal cord injuries admitted to Qingyang People’s Hospital from May 2017 to May 2019 were randomly divided into hyperbaric oxygen (HBO) group and control group, with 75 cases in each group, according to random number table method. The patients in both groups were given basic conventional treatment, and HBO treatment was added to the patients in the HBO group. The clinical efficacy and Frankel grades of neurological function before and after treatment were observed. The data of age, injury site, injury reason, injury severity, starting time of the postoperative HBO treatment, and times of HBO treatment in the HBO group were collected and analyzed by Logistic regression analysis for studying the risk factors affecting HBO clinical efficacy.Results:The total effective rate of the HBO group (88.00%) was significantly higher than that of the control group (61.33%) ( P < 0.01); after treatment, the proportion of Grade A patients in the HBO group (2.67%) was significantly lower than that of the control group (13.33%), while the proportion of Grade E patients (28.00%) in the HBO group was significantly higher than that of the control group (12.00%), with statistically significant difference ( P < 0.05). The injury severity, the starting time of postoperative HBO treatment, and the times of HBO treatment were the influencing factors of the HBO clinical efficacy for the patients with spine and spinal cord injuries ( P<0.05 or P<0.01). Logistic regression analysis showed that the starting time of postoperative HBO treatment was the risk factor of the HBO clinical efficacy ( P < 0.05). Conclusion:HBO can achieve an obvious efficacy in treating spine and spinal cord injuries by significantly promoting the recovery of neurological function. The starting time of postoperative HBO treatment is a risk factor of the HBO treatment of spine and spinal cord injuries. It suggests that HBO treatment should be carried out within 8 hours after operation, which can be more conducive to the recovery of neurological function.
