Advances in the Use of Tacrolimus for Adverse Reactions After Renal Transplantation
10.3870/j.issn.1004-0781.2025.10.003
- VernacularTitle:肾移植术后他克莫司所致主要不良反应的研究进展
- Author:
Jiaxin LI
1
;
Rui ZHANG
1
;
Yani LLU
1
;
Shaojun SHL
1
Author Information
1. 华中科技大学同济医学院附属协和医院药学部,武汉 430022
- Publication Type:Journal Article
- Keywords:
Tacrolimus;
Renal transplantation;
Adverse drug reactions
- From:
Herald of Medicine
2025;44(10):1541-1549
- CountryChina
- Language:Chinese
-
Abstract:
Renal transplantation is one of the main treatment methods for end-stage renal disease,and tacrolimus(TAC)is an immunosuppressant widely used in renal transplantation,to achieve anti-transplant rejection by inhibiting T cell activation and proliferation.However,in addition to the significant efficacy.TAC has a series of adverse reactions in the application of renal transplantation,including nephrotoxic-related diseases,cardiovascular diseases,neurological diseases,etc.Therefore,it is important to take corresponding management measures to improve the effectiveness of TAC.On the basis of previous studies on adverse reactions,this article aims to provide reference and guidance for further clinical practice of rational drug use after renal transplantation.
