Health Economics Evaluation of Urban Lung Cancer Screening in Anhui Province Based on Markov Modeling
10.11735/j.issn.1004-0242.2025.02.A007
- VernacularTitle:基于Markov模型的安徽省城市肺癌筛查卫生经济学评价研究
- Author:
Li WANG
1
;
Huiting LIU
;
Liting QIAN
;
Donghua WEI
;
Yanling MA
;
Mingming ZOU
;
Debin WANG
;
Jing CHAI
Author Information
1. 安徽医科大学卫生管理学院,安徽 合肥 230032
- Publication Type:Journal Article
- Keywords:
low-dose computed tomography;
screening;
cost-effectiveness analysis;
cost-utility analysis;
Anhui
- From:
China Cancer
2025;34(2):132-137
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the cost-effectiveness and cost-utility conducted on the lung can-cer screening project in urban areas of Anhui Province,and to provide suggestions for the formu-lation of lung cancer screening policies in Anhui Province.[Methods]A Markov decision model for low-dose computed tomography(LDCT)lung cancer screening intervention was established based on on-site survey data and literature data.The development of the population under different interventions was simulated,using saved life years(LYS)and quality-adjusted life years(QALY)as effectiveness indicators,to conduct cost-effectiveness and cost-utility analyses of different screening strategies.Cost data were discounted at a 3％discount rate.[Results]The screening schemes of once a year,once every two years,once every three years,and once every five years all meet the cost-effectiveness principle for saving one LYS or QALY.Among them,the best screening strategy in terms of cost-effectiveness and cost-utility was the LDCT lung cancer screening strategy once every two years,with costs of 72 441.54 CNY and 71 050.24 CNY,respectively.[Conclusion]The LDCT lung cancer screening program demonstrates good cost-effectiveness,with strategies of dif-ferent screening frequencies being viable options.The optimal screening strategy is screening once every two years.
