Trends of Incidence and Age at Onset of Leukemia in Jiangsu Cancer Registration Areas from 2009 to 2019
10.11735/j.issn.1004-0242.2025.02.A006
- VernacularTitle:2009-2019年江苏省肿瘤登记地区白血病发病趋势及年龄变化特征分析
- Author:
Haiyan LU
1
;
Xinxin DONG
;
Xingxing ZHU
;
Dekun ZHANG
;
Yuxue YANG
;
Xiaolan ZHAO
;
Renqiang HAN
;
Jinyi ZHOU
;
Ran TAO
;
Weigang MIAO
;
Pengfei LUO
Author Information
1. 泰州市疾病预防控制中心,江苏泰州 225300
- Publication Type:Journal Article
- Keywords:
leukemia;
incidence;
trend analysis;
Jiangsu
- From:
China Cancer
2025;34(2):125-131
- CountryChina
- Language:Chinese
-
Abstract:
[Purpose]To analyze the trends of incidence and age at onset of leukemia in Jiangsu cancer registration areas from 2009 to 2019.[Methods]The continuous monitoring data of leukemia from 2009 to 2019 were collected from 16 cancer registries in Jiangsu Province.All datasets were checked and evaluated based on data quality control criteria and were included in the analysis.Crude incidence rate(CIR),age-standardized incidence rate by Chinese standard population(ASIRC),the average annual percentage change(AAPC),the standardized average age at onset,the changes in the age structure of incidence and the changes in the birth cohort by year were calculated.[Results]The incidence rate of leukemia significantly increased from 5.22/105 in 2009 to 7.88/105 in 2019,with a significant upward trend(for CIR,AAPC=4.95％,95％CI:3.82％～6.09％;for ASIRC,AAPC=2.97％,95％CI:1.52％～4.43％).The incidence rates were in-creased in all age groups and increased with the birth cohort by years.There was a tendency of backward shift for the age composition of the population,with the increasing of composition for those over 60 years old.The mean age at onset increased from 48.62 years old in 2009 to 57.96 years old in 2019,with a backward shift in the mean age(β=0.773,P＜0.001),and the mean age at onset increased with the year only in rural areas after standardization(β=0.428,P=0.017).[Conclusion]Leukemia incidence rate in Jiangsu Province increased from 2009 to 2019,and the age at onset has shifted backwards.It's important to strengthen the early prevention and control of leukemia.
