Contrast-enhanced ultrasound for evaluating blood supply pattern of pancreatic ductal adenocarcinoma
- VernacularTitle:超声造影评估胰腺导管腺癌血供模式
- Author:
Wanying JIA
1
;
Yang GUI
1
;
Xueqi CHEN
1
;
Tianjiao CHEN
1
;
Yuming SHAO
1
;
Xiaoyi YAN
1
;
Huanyu WANG
1
;
Hua LIANG
1
;
Tianrui YANG
1
;
Bo KONG
1
;
Jing ZHANG
1
;
Li TAN
1
;
Ke LYU
1
Author Information
- Publication Type:Journal Article
- Keywords: pancreatic neoplasms; ultrasonography; tomography,X-ray computed; blood supply
- From: Chinese Journal of Medical Imaging Technology 2024;40(12):1861-1866
- CountryChina
- Language:Chinese
- Abstract: Objective To observe the value of contrast-enhanced ultrasound(CEUS)for evaluating blood supply pattern of pancreatic ductal adenocarcinoma(PDAC).Methods A total of 210 single PDAC patients proved by pathology who underwent CEUS and contrast enhanced CT(CECT)examination were retrospectively enrolled.Blood supply patterns of PDAC,i.e.deficient or rich blood supply were evaluated based on findings of CEUS 25 s(CEUS-25 s)and 35 s(CEUS-35 s)after contrast agents injection and CECT,respectively.The evaluation results were compared among different methods.Disease free survival(DFS)and overall survival(OS)of patients with deficient and rich blood supply PDAC shown on CEUS-25 s were followed up and compared.Results CEUS-25 s found 60.00％(126/210)PDAC with deficient blood supply(poor blood supply group),while 40.00％(84/210)with rich blood supply(rich blood supply group).CEUS-35 s showed that the proportion deficient blood supply PDAC increased to 70.48％(148/210,P＜0.05),22 lesions changed from rich blood supply pattern on CEUS-25 s to deficient blood supply pattern.CECT displayed deficient blood supply in 91.90％(193/210)PDAC but rich blood supply in 8.10％(17/210)PDAC,both being significant different compared with results of CEUS-25 s and CEUS-35 s(both P＜0.05).Fifteen-five cases in deficient blood supply group and 39 in rich blood supply group completed 12(8,25)months'follow-up,and the median DFS of patients in deficient blood supply group and rich blood supply group was 8(6,10)and 12(7,17)months,respectively,with the median OS of 14(9,17)and 19(16,24)months,respectively.The median DFS and OS in poor blood supply group were both shorter than those in rich blood supply group(x2=17.227,27.166,both P＜0.001).Conclusion CEUS had important clinical value for evaluating blood supply pattern of PDAC.
