Influencing factors of short-term poor prognosis in patients with coronary heart disease and the pre-dictive value of AASI and TI
10.3969/j.issn.1008-0074.2024.06.13
- VernacularTitle:冠心病患者短期预后不良的影响因素及AASI、TI对其的预测价值
- Author:
Yu LI
1
;
Ling-yun NI
1
;
Yan XU
1
Author Information
1. 淮安市第二人民医院急诊科,江苏淮安 223001
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Angioplasty,balloon,coronary;
Prognosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2024;33(6):715-719
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This article aims to explore the influencing factors of short-term poor prognosis in patients with coronary heart disease(CHD)and the predictive value of ambulatory arterial stiffness index(AASI)and heart rate variability triangular index(TI).Methods:A total of 300 CHD patients treated in Huai'an Second People's Hos-pital between January 2019 and January 2022 were selected.According to incidence of major adverse cardiovascular events(MACE)during 6-month follow-up,they were divided into good prognosis group(n=210)and poor prog-nosis group(n=90).Clinical data,AASI and TI were compared between two groups.Multivariate Logistic regres-sion was used to analyze influencing factors of poor prognosis during 6-month follow-up in CHD patients;receiv-er operating characteristic(ROC)curve was used to analyze the predictive value of AASI and TI for poor prognosis during 6-month follow-up in CHD patients.Results:Compared with patients in good prognosis group,those in poor prognosis group had significant higher age,body mass index(BMI),high sensitive C reactive protein(hsCRP),low density lipoprotein cholesterol(LDL-C),fibrinogen(Fg),AASI,TI,and proportions of smoking history,diabetes history and multi-vessel coronary disease(P＜0.01 all).Multivariate Logistic regression indicated that AASI(OR=5.318,95％CI 1.728～16.372,P=0.004),TI(OR=3.463,95％CI 1.155～10.384,P=0.027),age(OR=1.912,95％CI 1.046～1.990,P=0.033),smoking history(OR=1.791,95％CI 1.089～1.844,P=0.006),diabetes history(OR=1.645,95％CI 1.008～1.793,P＜0.001),BMI(OR=1.732,95％Cl 1.013～1.242,P=0.030),hsCRP(OR=3.731,95％CI 1.466～6.454,P=0.017),LDL-C(OR=3.732,95％CI 1.546～9.424,P=0.023),Fg(OR=4.504,95％CI 2.253～11.012,P=0.007)and multi-vessel coronary disease(OR=5.054,95％CI 2.876～13.445,P=0.029)were independent risk factors for poor prognosis during 6-month follow-up in CHD patients.Compared with single detection of AASI(AUC=0.828)and TI(AUC=0.844),their combined detection had significant higher predictive value(AUC=0.916)for poor prognosis during 6-month follow-up in CHD patients(Z=2.503,2.030,P＜0.05 both).Conclusion:Age,basic medical history,inflammatory factors,blood lipid and number of diseased vessels could all affect the prognostic outcome of CHD pa-tients.AASI combined with TI has good predictive value for short-term prognosis in CHD patients.
