Effect of brain-computer interface on upper limb motor dysfunction in stroke patients based on functional near-infrared spectroscopy
10.3969/j.issn.1006-9771.2025.09.010
- VernacularTitle:基于功能性近红外光谱探讨脑机接口对脑卒中患者上肢运动功能障碍的效果
- Author:
Yunhan GAO
1
;
Shanshan HOU
1
;
Xinyu WANG
1
;
Chongtian ZHU
1
Author Information
1. 山东第二医科大学附属临沂市人民医院,山东 临沂市 276000;山东第二医科大学康复医学院,山东 潍坊市 261053
- Publication Type:Journal Article
- Keywords:
stroke;
brain-computer interface;
upper limb;
motor function;
functional near-infrared spectroscopy
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(9):1066-1073
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes in task-state brain region activation of stroke patients using functional near-infrared spectroscopy(fNIRS)in the treatment of upper limb motor function with brain-computer interfaces(BCI).Methods From April to October,2024,40 stroke patients in Linyi People's Hospital were randomly divided into control group and BCI group,with 20 cases in each group.Both groups received conventional rehabilitation therapy.The control group underwent low-frequency electrotherapy before conventional treatment,while BCI group received BCI therapy before conventional treatment,for four weeks.Fugl-Meyer Assessment-Upper Extremities(FMA-UE)and modified Barthel Index were used to evaluate the upper limbs motor function before and after treatment.A"wrist movement task"was designed to detect the level of oxyhemoglobin(HbO?)in the regions of interest(ROI)during the task.Results After treatment,the scores of MBI and FMA-UE increased in both groups(|t|>8.904,P<0.001),and were higher in BCI group than in the control group(|t|>2.584,P<0.05).The HbO? level in the premotor cortex/sup-plementary motor area(PMC/SMA)increased after treatment in BCI group(t=-3.965,P<0.01),and was high-er in BCI group than in the control group(t=-3.630,P<0.01).The difference of HbO? level in PMC/SMA be-fore and after treatment correlated with both the difference of MBI score(r=0.498,P<0.05)and the difference of FMA-UE score(r=0.799,P<0.001).Conclusion BCI can further improve the upper limb motor function of stroke patients on the basis of conventional treat-ment and enhance the cortical activation of PMC/SMA.
